Ongoing CARG Studies


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CARG Manuscripts


  1. Hurria A, Balducci L, Naeim A, Gross C, Mohile S, Klepin H, Tew W, Downey L, Gajra A, Owusu C, Sanati H, Suh T, Figin R. Mentoring junior faculty in Geriatric Oncology: A report from the Cancer and Aging Research Group. Journal of Clinical Oncology 2008; 26(19): 3125-3127.
  2. Hurria A, Togawa K, Mohile S, Owusu C, Klepin H, Gross C, Lichtman S, Gajra A, Bhatia S, Katheria V, Klapper S, Hansen K, Ramani R, Lachs M, Wong FL, Tew W. Predicting chemotherapy toxicity in older adults with cancer: A prospective 500 patient multi-center study. Journal of Clinical Oncology 2011;29(25):3457-65. PMID: 21810685.
  3. Dale W, Mohile SG, Eldadah BA, Trimble EL, Schilsky RL, Cohen HJ, Muss HB, Schmader KE, Ferrell B, Extermann M, Nayfield S, Hurria A, on behalf of the Cancer and Aging Research Group. Biological, Clinical, and Psychosocial Correlates at the Interface of Cancer and Aging Research. J Natl Cancer Inst 2012; 104(8): 581-589. PMID: 22457474.
  4. Mohile S, Dale W, Hurria A. Geriatric Oncology Research to Improve Clinical Care. Nat Reviews Clinical Oncology. 2012; 9(10):571-8. PMID:22825377.
  5. Hurria A, Mohile SG, Dale W. Research priorities in geriatric oncology: addressing the needs of an aging population. J Natl Compr Canc Netw. 2012;10(2):286-8. PMID: 22308521.
  6. Maggiore RJ, Gross CP, Togawa K, Tew WP, Mohile SG, Owusu C, Klepin HD, Lichtman SM, Gajra A, Ramani R, Katheria V, Klapper SM, Hansen K, Hurria A. Use of Complementary Medications among Older Adults with Cancer. Cancer 2012; 118(19):4815-23.PMID 22359348.
  7. Mohile SG, Hardt M, Tew W, Owusu C, Klepin H, Gross C, Gajra A, Lichtman SM, Feng T, Togawa K, Ramani R, Katheria V, Hansen K, Hurria A; Cancer and Aging Research Group. Toxicity of bevacizumab in combination with chemotherapy in older patients. Oncologist. 2013; 18(4): 408-14. PMID: 23576485. PMCID: PMC3639527.
  8. Weiss Wiesel TR, Nelson CJ, Tew WP, Hardt M, Mohile SG, Owusu C, Klepin HD, Gross CP, Gajra A, Lichtman SM, Ramani R, Katheria V, Zavala L, Hurria A; On behalf of the Cancer Aging Research Group (CARG). The relationship between age, anxiety, and depression in older adults with cancer. PsychoOncology 2014; DOI 10.1002/pon.3638. PMID: 25099337
  9. Hurria A, Dale W, Mooney M, Rowland JH, Ballman KV, Cohen HJ, Muss HB, Schilsky RL, Ferrell B, Extermann M, Schmader KE, Mohile SG. Designing Therapeutic Clinical Trials for Older and Frail Adults With Cancer: U13 Conference Recommendations. Journal of Clinical Oncology 2014; 32(24): 2587- 2594. PMID: 25071116
  10. Maggiore RJ, Dale W, Gross CP, Feng T, Tew WP, Mohile SG, Owusu C, Klepin HD, Lichtman SM, Gajra A, Ramani R, Katheria V, Zavala L, Hurria A; Cancer and Aging Research Group. Polypharmacy and potentially inappropriate medication use in older adults with cancer undergoing chemotherapy: effect on chemotherapy-related toxicity and hospitalization during treatment. Journal of the American Geriatrics Society 2014; 62(8): 1505-1512. PMID: 25041361
  11. Won E, Hurria A, Feng T, Mohile S, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Tew WP; Cancer and Aging Research Group. CA125 level association with chemotherapy toxicity and functional status in older women with ovarian cancer. International Journal of Gynecological Cancer 2013; 23(6); 1022-1028. PMID: 23765208
  12. Barginear MF, Muss H, Kimmick G, Owusu C, Mrozek E, Shahrokni A, Ballman K, Hurria A. Breast Cancer and aging: results of the U13 conference breast cancer panel. Breast Cancer Research and Treatment 2014; 146(1): 1-6. PMID: 24847891
  13. Gajra A, Klepin HD, Feng T, Tew WP, Mohile SG, Owusu C, Gross CP, Lichtman SM, Wildes TM, Chapman AE, Dotan E, Katheria V, Zavala L, Akiba C, Hurria A; Cancer and Aging Research Group (CARG). Predictors of chemotherapy dose reduction at first cycle in patients age 65 years and older with solid tumors. J Geriatr Oncol. 2015 Mar; 6(2): 133-40. doi: 10.1016/j.jgo.2014.12.002. Epub 2015 Feb 7.
  14. Owusu C, Cohen HJ, Feng T, Tew W, Mohile SG, Klepin HD, Gross CP, Gajra A, Lichtman SM, Hurria A; Cancer and Aging Research Group (CARG). Anemia and Functional Disability in Older Adults With Cancer. J Natl Compr Canc Netw. 2015 Oct; 13(10): 1233-9.
  15. Mohile SG, Velarde C, Hurria A, Magnuson A, Lowenstein L, Pandya C, O’Donovan A, Gorawara-Bhat R, Dale W. Geriatric assessment-guided care processes for older adults: A Delphi consensus of geriatric oncology experts. J Natl Compr Canc Netw. 2015 Sep; 13(9):1120-30. PubMed PMID: 26358796. PMCID: PMC4630807
  16. Hurria A, Mohile SG, Gajra A, Klepin HD, Muss H, Chapman A, Feng T, Smith D, Sun CL, De Glas N, Cohen H, Katheria V, Doan C, Zavala L, Levi A, Akiba C, Tew WP. Validation of a prediction tool for chemotherapy toxicity in older adults with cancer. J Clin Oncol. 2016 May 16. pii: JCO654327. PMID: 27185838
  17. Mohile SG, Hurria A, Cohen HJ, Rowland JH, Leah CR, Arora NK, Canin B, Muss HB, Magnuson A, Flannery M, Lowenstein L, Allore HG, Mustian KM, Demark-Wahnefried W, Extermann M, Ferrell B, Inouye SK, Studenski SA, Dale W. Improving the quality of survivorship for older adults with cancer. Cancer. 2016 May 12. doi: 10.1002/cncr.30053. PMID: 27172129
  18. Williams GR, Mackenzie A, Magnuson A, Olin R, Chapman A, Mohile S, Allore H, Somerfield MR, Targia V, Extermann M, Cohen HJ, Hurria A, Holmes H. Comorbidity in older adults with cancer. J Geriatr Oncol. 2015 Dec 22. PMID: 26725537
  19. Magnuson A, Allore H, Cohen HJ, Mohile SG, Williams GR, Chapman A, Extermann M, Olin RL, Targia V, Mackenzie A, Holmes HM, Hurria A. Geriatric assessment with management in cancer care: Current evidence and potential mechanisms for future research. J Geriatric Oncol. 2016; pii: S1879-4068(16)00055-2. doi: 10.1016/j.jgo.2016.02.007. PMID: 27197915
  20. Flannery M, Mohile SG, Dale W, Arora NK, Azar L, Breslau ES, Cohen HJ, Dotan E, Eldadah BA, Leach CR, Mitchell SA, Rowland JH, Hurria A. Interventions to improve the quality of life and survivorship of older adults with cancer: The funding landscape at NIH, ACS and PCORI. J Geriatric Oncol. 2016; pii: S1879-4068(16)00035-7. doi: 10.1016/j.jgo.2016.02.001. PMID: 27197917
  21. Karuturi M, Wong ML, Hsu T, Kimmick GG, Lichtman SM, Holmes HM, Inouye SK, Dale W, Loh KP, Whitehead MI, Magnuson A, Hurria A, Janelsins MC, Mohile S. Understanding cognition in older patients with cancer. J Geriatric Oncol. 2016 Jun 7. pii: S1879-4068(16)30030-3. doi: 10.1016/j.jgo.2016.04.004. PMID: 27282296
  22. Presley CJ, Dotan E, Soto-Perez-de-Celis E, Jatoi A, Mohile SG, Won E, Alibhai S, Kilari D, Harrison R, Klepin HD, Wildes TM, Mustian K, Demark-Wahnefried W. Gaps in nutritional research among older adults with cancer. J Geriatr Oncol. 2016 Jul 5. pii: S1879-4068(16)30032-7. doi: 10.1016/j.jgo.2016.04.006. PMID: 27197919
  23. Loh KP, Janelsins MC, Mohile SG, Holmes HM, Hsu T, Inouye SK, Karuturi MS, Kimmick GG, Lichtman SM, Magnuson A, Whitehead MI, Wong ML, Ahles TA. Chemotherapy-related cognitive impairment in older patients with cancer. J Geriatr Oncol. 2016 Jul 5. pii: S1879-4068(16)30034-0. doi: 10.1016/j.jgo.2016.04.008. PMID: 27197918
  24. Kilari D, Soto-Perez-de-Celis E, Mohile SG, Alibhai SM, Presley CJ, Wildes TM, Klepin HD, Demark-Wahnefried W, Jatoi A, Harrison R, Won E, Mustian KM. Designing exercise clinical trials for older adults with cancer: Recommendations from 2015 Cancer and Aging Research Group NCI U13 Meeting. J Geriatr Oncol. 2016 May 31. pii: S1879-4068(16)30033-9. doi: 10.1016/j.jgo.2016.04.007. PMID: 27197916
  25. Guerard EJ, Nightingale G, Bellizzi K, Burhenn P, Rosko A, Artz AS, Korc-Grodzicki B, Canin B, Dale W, Ferrell B. Survivorship care for older adults with cancer: U13 conference report. J Geriatr Oncol. 2016 Jul 6. pii: S1879-4068(16)30063-7. doi: 10.1016/j.jgo.2016.06.005. PMID: 27424802
  26. Nipp RD, Yao NA, Lowenstein LM, Buckner JC, Parker IR, Gajra A, Morrison VA, Dale W, Ballman KV. Pragmatic study designs for older adults with cancer: Report from the U13 conference. J Geriatr Oncol. 2016 Jul 5. pii: S1879-4068(16)00053-9. doi: 10.1016/j.jgo.2016.02.005. PMID: 27197914

CARG Abstracts


  1. Hurria A, Mohile S, Lichtman S, et al. Geriatric Assessment of Older Adults with Cancer: Baseline Data from a 500 Patient Multi-Center Study. J Clin Oncol, [Abstract 9546] ASCO Annual Meeting Proceedings, 2009.
  2. Hurria A, Togawa K, Mohile SG, Owusu C, Klepin D, Gross C, Lichtman SM, Katheria V, Klapper S, Tew WP. Predicting Chemotherapy Toxicity in Older Adults with Cancer: A Prospective 500 Patient Multicenter Study [Abstract 9001]. American Society of Clinical Oncology 2010. Oral presentation.
  3. Mohile SG, Hardt M, Tew WP, Owusu C, Klepin HD, Gross CP, Gajra A, Lichtman SM, Togawa K, Ramani R, Katheria V, Hansen K, Hurria A. Toxicity of Chemotherapy with Bevacizumab in Older Patients. [Abstract]. American Geriatric Society 2011. Presidential poster session.
  4. Maggiore RJ, Gross CP, Togawa K, Tew WP, Mohile SG, Klepin HD, Lichtman SM, Owusu C, Gajra A, Katheria V, Hansen K, Klapper S, Ramani R, Hurria A. Hebal and Complementary Medication Use among Older Adults with Cancer. [Abstract]. American Geriatric Society 2011.
  5. Klepin HD, Gajra A, Hardt M, Tew WP, Mohile SG, Owusu C, Gross CP, Lichtman SM, Ramani R, Katheria V, Brown J, Jayani R, Hansen K, Togawa K, Klapper S, Wong FL, Hurria A. Predictors of primary dose reduction (PDR) among patients age 65 and older receiving adjuvant chemotherapy. [Abstract 79650]. American Society of Clinical Oncology 2011. Oral presentation.
  6. Gajra A, Hardt M, Tew WP, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Ramani R, Brown J, Katheria V, Jayani R, Hansen K, Togawa K, Klapper S, Hurria A. Primary Dose Reduction (PDR) of Chemotherapy in Patients > Age 65 with Advanced Cancer and Toxicity Outcomes. [Abstract 74120]. American Society of Clinical Oncology 2011. Poster discussion.
  7. Maggiore RJ, Gross CP, Hardt M, Tew WP, Mohile SG, Klepin HD, Lichtman SM, Owusu C, Gajra A, Ramani R, Katheria V, Brown J, Jayani R, Hurria A. Polypharmacy, potentially inappropriate medications, and chemotherapy-related adverse events among older adults with cancer. [Abstract 84637]. American Society of Clinical Oncology 2011.
  8. Tew WP, Hardt M, Lichtman SM, Li D, Mohile SG, Owusu C, Klepin HD, Gross CP, Gajra A, Hurria A. Pre-Chemotherapy CA125 level is Associated with Poorer Functional Status and Chemotherapy Toxicity in Older Adults with Gynecologic Cancer. International Society of Geriatric Oncology 2011. Poster session.
  9. Trevino M, Sun CL, Nelson C, Hurria A, Klepin H. The Relationship Between Pre-treatment Psychological Distress and Days Hospitalized Among Older Adults Receiving Chemotherapy. Annual Conference of the American Psychosocial Oncology Society 2016.
  10. Weiss T, Nelson CJ, Tew WP, Hardt M, Mohile SG, Owusu C, Klepin HD, Gross CP, Gajra A, Lichtman SM, Ramani R, Katheria V, Zavala L, Hurria A, on behalf of the Cancer and Aging Research Group. The relationship among age, anxiety, and depression in older adults with cancer. [Abstract #99187]. American Society of Clinical Oncology 2012. Poster Session.
  11. Gajra A, Tew WP, Hardt M, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Katheria V, Hurria A, on behalf of the Cancer and Aging Research Group. Predictors of early discontinuation of chemotherapy (EDC) in patients (pts) ≥65 years with stage IV non-small cell lung cancer (NSCLC). [Abstract #93378]. American Society of Clinical Oncology 2012. Poster Session.
  12. Klepin HD, Pitcher B, Ballman KV, Kimmick GG, Kornblith AB, Cohen HG, Hurria A, Winer EP, Hudis C, Muss HB. Comorbidity, chemotherapy toxicity, and outcomes among older women receiving adjuvant chemotherapy for breast cancer (BC). American Society of Clinical Oncology 2012. Poster Session.
  13. Owusu C, Tew W, Hardt M, Mohile S, Klepin H, Gross C, Gajra A, Lichtman S, Ramani R, Hurria A. Anemia and functional disability in older adults with cancer. American Society of Clinical Oncology 2012. Poster Session.
  14. Hurria A, Hardt M, Tew WP, Mohile SG, Owusu C, Gross CP, Gajra A, Lichtman SM, Katheria V, Ramani R, Zavala L, Klepin HD. Factors associated with life expectancy (LE)<3 months (mo) among older adults receiving palliative chemotherapy (chemo.) American Society of Clinical Oncology 2012. Poster Session.
  15. Hsu T, Nathwani N, Loscalzo M, Ferrell B, Chung V, Chao J, Karanes C, Koczywas M, Forman S, Lim D, Siddiqi T, Stein A, Twardowski P, Nademanee A, Pal S, Hein M, Akiba C, Goldstein L, Smith D, Hurria A. Quality of life (QOL) of caregivers of adults, age 65 and older, with cancer admitted to hospital. 2014 MASCC International Symposium on Supportive Care in Cancer. Oral presentation.
  16. Muss H, Deal A, Hurria A, Mitin N, Torrice C, Janakiraman K, Jolly T, Williams G, Alston S, West J, Zavala L, Katheria A, Sharpless N. p16INK4a Expression and Chemotherapy Toxicity in Women with Early Stage Breast Cancer. San Antonio Breast Cancer Symposium 2014. Poster Session.
  17. Peterson LL, Hurria A, Feng T, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Glezerman IG, Katheria V, Zavala L, Smith DD, Tew WP. Association between renal function and chemotherapy-related toxicity in older adults with cancer. American Society of Clinical Oncology Annual Meeting 2015. Oral Presentation.
  18. Wildes TM, Tew WP, Maggiore RJ, Edwards B, Cohen HJ, Smith D, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Katheria V, Akiba C, Hurria A. Association of geriatric assessment factors with falls in older adults initiating chemotherapy. American Society of Clinical Oncology Annual Meeting 2015. Poster Session.
  19. Hsu T, Loscalzo M, Ramani R, Forman SJ, Popplewell L, Clark KL, Katheria V, Strowbridge R, Rinehart R, Matthews K, Dillehunt J, Feng T, Smith D, Hurria A. Differences between patient and caregiver assessments and their association with caregiver burden in caregivers of older adults with cancer. American Society of Clinical Oncology Annual Meeting 2015. Poster Session.
  20. Trevino M, Sun CL, Nelson C, Hurria A, Klepin H. The Relationship Between Pre-treatment Psychological Distress and Days Hospitalized Among Older Adults Receiving Chemotherapy. Annual Conference of the American Psychosocial Oncology Society 2016. Oral Presentation.
  21. Klepin HD, Sun CL, Smith D, Elias R, Trevino KM, Bryant AL, Nelson CJ, Tew WP, Mohile SG, Owusu C, Gross CP, Gajra A, Lichtman SM, Katheria V, Hurria A. Predictors of unplanned hospitalizations among older adults receiving cancer chemotherapy. American Society of Clinical Oncology Annual Meeting 2016. Poster Session.
  22. Shahrokni A, Sun CL, Tew WP, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Katheria V, Cohen HJ, Hurria A. Complex association between social support and chemotherapy-related toxicities in older cancer patients. American Society of Clinical Oncology Annual Meeting 2016. Poster Session.