The overall goal of this NIA-funded five-year R21/R33 grant, "Cancer and Aging Research Group (CARG) Infrastructure Grant," is: to develop a sustainable national research infrastructure to create and support significant and innovative projects addressing key interdisciplinary research questions at the aging and cancer interface.

Specific Aims:

  1. Solidify the infrastructure and expertise, in the form of Cores, needed to facilitate the design of impactful aging and cancer research based on U13 priorities
  2. Utilize the sustainable infrastructure to foster collaborations among a range of interdisciplinary investigators across the nation to accelerate innovative research in aging and cancer
  3. Support and guide high-priority research projects at the interface of aging and cancer to lay the foundation for competitive multi-site studies
  4. Identify, cultivate, and mentor investigators in aging and cancer research
  5. Disseminate through effective communication strategies the research findings and data-sharing opportunities to the larger community

Principal Investigators:

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William Dale, MD, PhD
Principal Investigator
Arthur M. Coppola Family Chair in Supportive Care Medicine
City of Hope
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Arti Hurria, MD
Principal Investigator
George Tsai Family Chair in Geriatric Oncology
City of Hope
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Supriya Mohile, MD, MS
Principal Investigator
Professor of Medicine and Surgery
James Wilmot Cancer Institute, University of Rochester

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The 1st CARG Infrastructure Grant Conference was held on October 4-5th, 2018 at City of Hope, Duarte, CA. We have made available the summary slides to help provide additional details at the conference and the video recordings to the conference:

Conference Presentation Slides:
  1. SCOREboardPatient Advocate Board Presentation
  2. Building the Infrastructure
  3. Delphi Survey Results
  4. Welcome - Day 1 Introduction to the CARG Infrastructure Grant
  5. Conference Wrap-Up
  6. Core 1 and 2: Clinical and Biological Measures of Aging
  7. Core 3: Behavioral, Psychological, & Supportive Care Intervention
  8. Core 4: Care Delivery & Comparative Effectiveness Research
  9. Core 5: Epidemiology, Biostatistics, & Informatics
  10. Core 6: Dissemination and Communication

Video Recordings:

Day 1 - Morning Session

Day 1 - Afternoon Session

Day 2

Contact Us:

For any questions or inquiries about the grant, please reach out to the CARG Infrastructure Grant Team at:

Telephone: 626-218-0861

U13 Grant

The U13 grant, “Geriatric Oncology Research to Improve Clinical Care,” is a cooperative conference grant between the Cancer and Aging Research Group in collaboration with the Geriatrics and Clinical Gerontology branch of the National Institute on Aging (NIA) and the National Cancer Institute (NCI). The mission of this conference grant program is to provide a forum for a multidisciplinary team of investigators in geriatrics and oncology to review the present level of evidence in geriatric oncology, identify areas of highest research priority, and develop research approaches to improve clinical care for older adults with cancer within the next 10 years.

The Goals of the Conference Grant

The goals of the conference grant are:
1. To identify the present level of evidence and areas of high research priority in geriatric oncology
2. To identify strengths in research methodology, from fields of geriatrics and oncology, that can be applied and integrated into research studies involving older adults with cancer
3. To foster collaboration between multidisciplinary scholarly teams, with a focus on shared research methods to be utilized across studies in geriatric oncology
4. To foster and promote the research of existing and new investigators in geriatric oncology
5. To disseminate findings from this conference grant program with easily adaptable recommendations to strengthen geriatric oncology research methodology


The topics for the conference series include:
1. Biological, Clinical, and Psychosocial Correlates at the Interface of Aging and Cancer Research
2. Design and Implementation of Therapeutic Clinical Trials for Older and/or/ Frail Adults with Cancer
3 .Design and Implementation of Intervention Studies to Maintain or Improve the Quality of Survival of Older and/or Frail Adults with Cancer.

The conference series is led by an Oversight Board consisting of members from the NIA, NCI, and CARG, as well as other organizations dedicated to geriatrics and/or oncology (AGS, ASCO, SIOG, AACR).

The Cancer and Aging Research Group Conference 2010 Agenda and Proceedings

The Cancer and Aging Research Group Conference 2012 Agenda and Proceedings

The Cancer and Aging Research Group Conference 2015 Agenda and Proceedings